药物性肝损害诊断标准及其临床应用

Diagnostic criteria of drug-induced liver injury and their clinical application

药物性肝损害是常见的药物不良反应之一。有1100种以上的药物和相关物质与药物性肝损害有关。然而,迄今药物性肝损害尚无特异性诊断标志。本文介绍和讨论几种主要的诊断标准,以期有助于临床药物性肝损害的诊断。

Drug-induced liver injury（DILI） is one of the common adverse drug reactions.Over 1100 drugs and related substances are associated with DILI.However,there is no specific diagnostic marker to DILI so far.This paper introduces and discusses some main diagnostic criterias in order to be helpful for diagnosis of DILI in clinical practice.