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髓过氧化物酶在冠心病中的诊断应用 被引量:1

The diagnostic application of myeloperoxidase in coronary artery disease
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摘要 大量研究证实,炎症促进了动脉粥样硬化的形成及发展,表现为粥样硬化斑块的形成.动脉硬化引起的危重心血管事件,如心肌梗死或缺血性脑卒中,为易损斑块破裂所导致[1].血制品中的蛋白或酶类通常作为生物标记物,反映疾病状态,并提供诊断及预后价值[2].
出处 《中国心血管病研究》 CAS 2011年第3期237-239,共3页 Chinese Journal of Cardiovascular Research
关键词 髓过氧化物酶 冠状动脉粥样硬化性心脏病 Myeloperoxidase( MPO ) Coronary heart disease
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参考文献23

  • 1Weber C, Zernecke A, Libby P. The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models. Nature Reviews Immunology, 2008,8 : 802-815.
  • 2吴志婷,梅拥军,曹平良,曾黎峰,尹秋林,盛国太,葛郁芝.炎性因子与急性冠状动脉综合征相关性研究[J].中国心血管病研究,2008,6(10):732-734. 被引量:8
  • 3李惠,包宗明.髓过氧化物酶及其多态性与冠状动脉疾病的研究进展[J].中国心血管病研究,2007,5(1):70-72. 被引量:13
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二级参考文献81

共引文献24

同被引文献7

  • 1Ndrepepa G,Braun S,Mehilli J,et al.Myeloperoxidase levelin patients with stable coronary artery disease and acute coro-nary syndrome[J].Eur J Clin Invest,2008,38(2):90-96.
  • 2Vander Zee PM,Bio E,Ko Y,et al.P-selectin and CD63-expo-sing platelet microparticles reflect platelet activation in periph-eral arterial disease and myocardial infarction[J].Clin Chem,2006,52(4):657-664.
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  • 5Hochholzer W,Morrow DA,Giugliano RP.Novel biomarkersin cardiaovascular disease:update 2010[J].Am Heart J,2010,160(4):583-594.
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  • 7方金瑞,魏小国,马丽雅.原发性高血压患者颈总动脉超声等临床变量与髓过氧化物酶基因变异的关系[J].临床心血管病杂志,2010,26(10):737-740. 被引量:1

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