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活体肝细胞磷31磁共振波谱数据分类 被引量:1

Classification of ^(31)phosphorus magnetic resonance spectroscopy data for liver cell in vivo
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摘要 基于活体肝细胞的31P磁共振波谱图(31Phosphorus Magnetic Resonance Spectroscopy,31P-MRS)对肝细胞数据进行诊断,分为3种类型:肝癌、肝硬化和正常肝。分别运用线性分类器和二次分类器对数据分类,并在分类前进行了特征抽取。线性分类器和二次分类器在"留一法"中对上述3种类型的分类准确率分别约为81.37%、77.75%、92.30%和95.27%、99.89%、99.70%。实验证明二次分类器相对于线性分类器,明显地提高了分类准确率。 Data based on ^31 phosphorus magnetic resonance spectroscopy map of liver cells in vivo are divided into three diagnostic types of hepatocellular carcinoma,hepatic cirrhosis and normal hepatic tissue.The data are classified using linear classifier and quadratic classifier separately,and main features are selected before classification.Classification accuracy rate of the data in leave-one-out method when linear classifier and quadratic classifier are used are about 81.37%、77.75%、92.30% and 95.27%、99.89%、99.70% separately.Experiments prove that the classification accuracy rate of the data when quadratic polynomial classifier is used is obviously improved,compared to linear classifier.
出处 《计算机工程与应用》 CSCD 北大核心 2011年第9期236-239,共4页 Computer Engineering and Applications
基金 山东省自然科学基金(No.Y2006C96 No.Y2008G30) 山东省教育厅高等学校科研计划项目(No.G07WG17) 山东省医药卫生科技发展项目(No.2009HZ081)~~
关键词 31P 磁共振波谱 线性判别分析 二次分类器 ^ 31phosphorus magnetic resonance spectroscopy linear discriminant analysis quadratic classifier
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参考文献15

  • 1李保朋,刘强.磁共振波谱技术在肝脏肿瘤中的研究现状及发展趋势[J].医学影像学杂志,2008,18(12):1461-1463. 被引量:7
  • 2陈星荣 蕈炳鳞 沈天真.磁共振波潜分析(一).上海生物医学工程,.
  • 3Lenkinski R E.MR spectroscopy:Clinical tool or research probe? (Revisited) [J].Academic Radiology, 2001,8(7) : 567-570.
  • 4Lens P N L,Hemminga M A.Nuclear magnetic resonance in environmental engineering: Principles and applications[J].Biodegradation, 1998,9(6) : 393-409.
  • 5Mierisova S M R.Spectroscopy quantitation:A review of frequency domain methods[J].NMR in Biomedicine, 2001,14(4) : 247-259.
  • 6Menon D K, Sargentoni J, TaylorRobinson S D, et al,Efl'ect offunctional grade and etiology on in vivo hepatic phosphorus31 magnetic resonance spectroscopy in cirrhosis: Biochemical basis of spectral appearances[J].Hepatology, 1995,21(2).
  • 7柴晓路.Web服务架构与开放互操作技术[M].北京:清华大学出版社,2003.
  • 8Fisher R A.Yhe statistical utilization of multiple measuerments[J]. Annals of Eugenics, 1938,8 : 376-386.
  • 9Schwardt L.TW414/PR813 lecture 1 manipulating feature space[EB/OL]. (2003) .http ://dsp.ee.sun.ac.za/schwardt/pr813/lectures/ lecture01/.
  • 10Fukunaga K.Introduction to statistical pattern recognition[M].[S.l.]: Academic Press, 1990.

二级参考文献35

  • 1刘强,王滨,武乐斌.^(31)PMR波谱分析在肝细胞癌、肝硬化及正常肝组织中的临床应用价值[J].实用放射学杂志,2005,21(5):493-496. 被引量:14
  • 2韩争胜,李映,张艳宁.基于LDA算法的人脸识别方法的比较研究[J].微电子学与计算机,2005,22(7):131-133. 被引量:20
  • 3刘于宝,梁长虹,张忠林,余元新,谢淑飞,林韩斌,王秋实,郑君惠.^(31)P MR波谱成像在肝脏的初步临床应用研究[J].实用放射学杂志,2006,22(4):417-420. 被引量:11
  • 4Castillo M, Kwoek L, Mukherji SK. Clinical applications of proton MR spectroscopy[J]. AJNR, 1996,17 : 1 - 15.
  • 5Danielsen ER, Ross B. Magnetic resonance spectroscopy diagnosis of neurological diseases. Danielsen ER & Ross B. (eds.), Marcel Dekker, Inc New York, 1998,5- 22.
  • 6Taylor-Tobinson SD. Applications of magnetic resonance spectroscopy to chronic liver disease[J]. Clin Med, 2001,1:54 - 60.
  • 7Towner RA, Foley LM, Painter DM. Hepatocarcinogenesis tumor grading correlated with in vivo image-guided ^1H-NMR spectroscopy in a rat medel[J]. Toxicol Appl Pharmacol,2005,207:237- 244.
  • 8Spper R, Himmelreich U, Painter D, et al. Patholoy of hepatocellular carcinoma and its precursors using proton magnetic resonance spectroscopy and a statistical classification strategy[J]. Pathology, 2002, 34:417 - 422.
  • 9Yang Y, Li C, Nie X, et al. Metabonomic studies of human hepatocellular carcinoma using high-resolution magic-angle spinning ^1H-NMR spectroscopy in conjunction with multivariate data analysis [ J ]. Protcome Res,2007,6:2605 - 2614.
  • 10Kamm YJ, Heerschap A, van den Bergh EJ, et al. ^19F-maglletie resonance spectroscopy in patients with liver metastases of colorectal cancer treated with 5-fluorouracil[J]. Anticancer Drugs,2004,15:229 - 233.

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