育肥猪呼吸道疾病综合征病理学观察和病原学检测

Pathological examination and pathogen detection of porcine respiratory disease complex in a finisher swine herd

猪呼吸道疾病综合征是一种由病毒、细菌、环境应激和猪体免疫力低下等多因素相互作用引起的呼吸道疾病。2009年2～4月,上海农场某猪场一批育肥猪出现疑似病例,表现为食欲下降,咳嗽,呼吸困难,生长缓慢和料肉比降低。本研究在流行病学调查的基础上,剖检8头病猪观察其病理变化,主要表现为肺脏弥慢性实变,弹性降低,间质增宽,有的水肿、气肿,或纤维素性胸膜肺炎。病原检测结果显示,该发病猪群主要病原为猪繁殖与呼吸综合征病毒、猪圆环病毒2型和副猪嗜血杆菌。本研究为猪呼吸道疾病综合征的防治提供了依据。

The porcine respiratory disease complex （PRDC） is a complex disease caused by many factors, including virus, bacteria, environmental stress and low immunity. Some cases snsceptive of PRDC were found in a swine farm of Shanghai in April 2009. The pigs showed anorexia, cough, dyspnea, slow growth and reduction of feed efficiency. After epidemiologicat investigation, eight fattening pigs with respiratory syndrome were selected for gross pathological analysis. The lungs showed mainly diffused consolidation, reduced flexibility, interstitial thicking, emphysema or fibrinous pleuropneumonia. The results of pathogen detection showed that these pigs were mainly infected with porcine reproductive and respiratory syndrome virus （PRRSV） , porcine circovirus type 2 （ PCV2 ） and Haemophilus parasuis （Hps）. This study would be useful for the prevention and control of PRDC.