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血管生成拟态在骨肉瘤中的研究进展

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摘要 血管生成拟态（vasculogenic mimicry,VM）是指高度恶性肿瘤细胞模拟血管内皮细胞形成的一种具有输送血液的管道结构,是近年发现的一种全新的肿瘤微循环模式.
作者 练文兴 石宇雄 赖智敏
机构地区 广州中医药大学第二临床医学院 广州市番禺区中医院骨科
出处 《中国骨肿瘤骨病》 2011年第1期70-73,共4页 Chinse Journal Of Bone Tumor And Bone Disease
基金 广东省科技厅社会发展领域科技计划项目(编号:83031)
关键词 血管生成拟态 骨肉瘤 恶性肿瘤细胞 肿瘤微循环 细胞形成 血管内皮
分类号 R738.1 [医药卫生—肿瘤]
  • 相关文献

参考文献11

  • 1Hess AR,Seftor EA,Gardner LM,et al.Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation:role of epithelial cell kinase (Eck/EphA2).Cancer Res,2001,61:3250-3255.
  • 2Hendrix MJ,Seftor RE,Seftor EA,et al.Transendothelial function of human metastatic melanoma cells:role of the microenvironment in cell-fate determination.Cancer Res,2002,62:665-668.
  • 3Sun B,Zhang D,Zhang S,et al.Hypoxia influences vasculogenic mimicry channel formation and tumor invasion-related protein expression in melanoma.Cancer Lett,2007,249:188-197.
  • 4Hess AR,Seftor EA,Seftor RE,et al.Phosphoinositide 3-kinase regulates membrane type 1-matrix metalloproteinase (MMP) and MMP-2 activity during melanoma cell vasculogenic mimicry.Cancer Res,2003,63:4757-4762.
  • 5Hendrix MJ,Seftor RE,Seftor EA,et al.Transendothelial function of human metastatic melanoma cells:role of the microenvironment in cell-fate determ ination.Cancer Res,2002,62:665-668.
  • 6Hess AR,Seftor EA,Seftor RE,et al.Phosphoinositide 3-kinase regulates membrane Type l-matrix metalloproteinase (MMP) and MMP-2 activity during melanoma cell vasculogenic mimicry.Cancer Res,2003,63:4757-4762.
  • 7Folberg R,Maniontis AJ.Vasculogenic mimicry (Review).APMIS,2004,112:508-525.
  • 8高启龙,陈永强,李柏,凌昌全.蜂毒素抗骨肉瘤裸鼠移植瘤的作用及对肿瘤血管生成拟态的影响[J].肿瘤,2008,28(9):771-775. 被引量：15
  • 9尧良清,丰有吉,丁景新,徐丛剑,金鸿雁,殷莲华.缺氧诱导卵巢上皮性癌细胞形成拟态血管的前期研究[J].中华妇产科杂志,2005,40(10):662-665. 被引量：27
  • 10梅炯,贾永伟,蔡宣松.Vascular Channel Formation by Osteosarcoma Cells in Vitro: Vasculogenic Mimicry[J].The Chinese-German Journal of Clinical Oncology,2003,2(4):237-239. 被引量：2

二级参考文献23

  • 1尧良清,丰有吉,丁景新,徐丛剑,金鸿雁,殷莲华.缺氧诱导卵巢上皮性癌细胞形成拟态血管的前期研究[J].中华妇产科杂志,2005,40(10):662-665. 被引量：27
  • 2赵静,黄江生,杨爱军,王晨昱,刘伟,李敏.肝细胞癌中血管生成拟态的三维细胞培养及组织学研究[J].癌症,2007,26(2):123-126. 被引量：24
  • 3Maniotis AJ, Folberg R, Hess A, et al. Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry. Am J Pathol, 1999, 155:739-752.
  • 4Folberg R, Maniotis AJ. Vasculogenic mimicry. APMIS, 2004, 112:508-525.
  • 5Shirakawa K, Wakasugi H, Heike Y, et al. Vasculogenic mimicry and pseudo-comedo formation in breast cancer. Int J Cancer, 2002, 99:821-828.
  • 6Sharma N, Seftor RE, Seftor EA, et al. Prostatic tumor cell plasticity involves cooperative interactions of distinct phenotypic subpopulations: role in vasculogenic mimicry. Prostate, 2002, 50:189-201.
  • 7Hendrix MJ, Seftor EA, Hess AR, et al. Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma. Nat Rev Cancer, 2003, 3:411-421.
  • 8Choi KS, Bae MK, Jeong JW, et al. Hypoxia-induced angiogenesis during carcinogenesis. J Biochem Mol Biol, 2003, 36:120-127.
  • 9Humar R, Kiefer FN, Berns H, et al. Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling. FASEB J, 2002, 16:771-780.
  • 10CaiXS ,,MeiJ,LiRL ,etal.Clinicalsignificanceofmicrovesseldensityinosteosarcoma[].JClinOrthopaedics.1999

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中国骨肿瘤骨病
2011年 第1期

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