64层螺旋CT对冠状动脉粥样硬化血管狭窄的评价

Assessment of Coronary Atherosclerotic Stenosis with 64-slice Spiral CT

目的:探讨64层螺旋CT对冠状动脉粥样硬化各种程度血管狭窄的评估价值。方法:120例患者行64层螺旋CT血管造影(CTA)检查评价冠状动脉各段的狭窄程度,并与冠状动脉血管造影(CAG)比较,统计64层螺旋CTA诊断冠状动脉各种程度狭窄的敏感性、特异性、阳性预测值(PPV)和阴性预测值(NPV)。结果:64层螺旋CTA评估冠状动脉轻度、中度和重度狭窄的敏感性、特异性、PPV和NPV随着狭窄程度的增加而增高,敏感性分别为79.55%、84.42%和87.50%,特异性分别为99.48%、99.57%和99.74%,PPV分别为92.11%、92.86%和94.23%,NPV分别为98.45%、98.97%和99.40%。结论:64层螺旋CT对冠状动脉粥样硬化血管狭窄程度的评价具有重要的临床诊断价值,可作为有效的冠心病筛查工具以及选择治疗方案的重要参考。

Purpose：To study the value of 64-slice spiral CT in the assessment of the coronary atherosclerotic stenosis.Methods： Coronary CT angiographys（CTA） of 120 patients were performed with 64-slice spiral CT.All CTA images of coronary arteries which were compared with coronary angiography were reconstructed and analyzed.The sensitivity,specificity,positive predictive value（PPV） and negative predictive value（NPV） of the diagnosis ability in the coronary atherosclerotic stenosis with 64-slice spiral CT were calculated.Results：With the increasing of the stenosis degree which was divided into mild,moderate and severe stenosis,the sensitivity,specificity,PPV and NPV of the diagnosis ability in the coronary atherosclerotic stenosis with 64-slice spiral CT were increased.The sensitivity was 79.55%,84.42% and 87.50%,respectively.The specificity was 99.48%,99.57% and 99.74%,respectively.The PPV was 92.11%,92.86% and 94.23%,respectively.The NPV was 98.45%,98.97% and 99.40%,respectively.Conclusion：The assessment of the coronary atherosclerotic stenosis with 64-slice spiral CT shows clinical significance.Coronary CTA could be a effective tool in diagnosing coronary heart disease and a significant reference in selecting treatment program.