自然感染日本血吸虫病耕牛血清循环抗原消长规律的研究

THE STUDY OF THE DETECTING OF SERUM CIRCULATING ANTIGENS IN FARM CATTLES NATURALLY INFECTED WITH SCHISTOSOMA JAPONICA

为了观察疫区自然感染日本血吸虫病耕牛血清循环抗原消长规律，本试验将血吸虫病非疫区的水、黄牛各１０头，转运至安徽省血吸虫病疫区，接受为期８周的自然感染。用斑点酶联免疫吸附试验测定牛血清循环抗原。结果，水、黄牛血清循环抗原滴度均于自然感染第４周后明显上升，水、黄牛自然感染第８周的血清循环抗原最高滴度分为１∶１０２４０和１∶５１２０，最低滴度则分别为１∶１２８０和１∶６４０，水牛循环抗原滴度高于黄牛。虫荷数与血清循环抗原滴度未见有相关性。

For observing the detecting of serum circulating antigens in farm cattles naturally infected with Schistosoma Japonica in the endemic area, 10 buffaloes and 10 yellow cattles from non endemic area were transferred to the Schistosomasis endemic area in Anhui province and grazed there for 8 weeks. The titre of serum circulating antigens of cattles was increased significantly at the fourth week after grazing detected by DOT ELISA. At the eighth week post grazing, the titre of serum circulating antigens of water baffeloes (the highest is 1∶102 240 and the lowest is 1∶1 280)was higher than that of yellow cattles (the highest is 1∶5 120 and the lowest is 1∶640). There is no relation between the worm burden and the titre of serum circulating antigens of animals was observed.