391例上消化道出血临床特点分析

Clinical Analysis on 391 Cases of Upper Gastrointestinal Bleeding

目的：探讨分析上消化道出血的临床特点.方法：对2006～2010年391例上消化道出血患者临床资料进行回顾性调查分析.结果：391例上消化道出血主要原因为消化性溃疡269例,（占68.8%））;胃食管恶性肿瘤51例（占13%）占;食道胃底静脉曲张破裂出血36例（占9.1%）;糜烂出血性胃炎20例（占5.1%）,吻合口溃疡5例（占1.2%）;Dieulafoy病3例（占0.8%）;十二指肠球炎2例（占0.5%）;Mallory-Weiss综合征1例（占0.3%）;食管溃疡1例（占0.3%）;胆道出血1例（占0.3%） ;钩虫病1例（占0.3%）;过敏性紫癜1例（占0.3%）.结论：急诊胃镜检查是诊断上消化道出血原因的最好方法;消化道出血主要为消化性溃疡.出血的原因主要是胃酸及蛋白酶、胆酸、非甾体消炎药等破坏因素及胃粘膜保护因子平衡紊乱引起.

Objective To explore the clinical characteristics of upper gastrointestinal hemorrhage. Met, hods A retrospective review of clinical records of 391 patients referred for UGIB between 2006--2010 was performed. Resuhs The main causes of 391 cases of upper gastrointestinal hemor- rhage were peptic ulcer （68.8%）, esophageal and gastric carcinoma （13%）, esophageal varicosity （9.1%） , gastrointestinal membrane trauma （5. 1% ）, anastomotic ulcer（1.2%）, Dieulafoy disease （0.8%）, duodenitis （0.5%）, Mallory -- Weiss syndrome （0.3%）, esophageal ulcer（0.3%）, hemobilia （0.3 %）, ancylostomiasis （0.3%） and Henoch--Schonlein purpura （0.3%） . Conclusion Emergent gastroscopy is the bestand effectivemethod for determining causes of upper gastro intestinal hem-orrhage. Gastrointestinal bleeding iscaused mainly by peptic ulcer. The main cause is the disturbance of balance in gastric acid, cholic acid,pepsin and gastricmu--cosa protective factor.