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肠缺血再灌注中的MAPKs信号转导通路 被引量:3

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摘要 肠缺血再灌注(intestinal ischemia reperfusion,IIR)损伤是常见的组织器官损伤之一,它在严重感染、外伤、休克、心肺功能不全、器官移植等的过程中起重要作用。其机制主要为缺血一段时间后,组织适应了低氧环境的新陈代谢,血流的回复导致激活血管内巨噬细胞,继而相应的生成活性氧自由基(ROS),ROS又诱发内皮损伤,
出处 《中国实用医药》 2011年第6期249-251,共3页 China Practical Medicine
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