更昔洛韦与利巴韦林治疗小儿手足口病的疗效比较

Ganciclovir and comparison of the curative effect of ribavirin in treatment of infantile hand foot and mouth disease

目的:观察更昔洛韦治疗手足口病的效果。方法:将82例住院手足口病患儿按就诊顺序随机分为两组,观察组42例更昔洛韦静脉滴注;对照组40例利巴韦林静脉滴注,两组总有效率观察组为97.62%,对照组75%,两组比较差异有统计学意义(P<0.05)。结论:更昔洛韦治疗手足口病,临床症状消退时间,临床疗效较利巴韦林好,安全性较高,值得临床推广使用。

Objective：To evaluate the effect of Ganciclovir for hand-foot-mouth disease.Methods：Eighty-two patients from our hospital were randomly divided into two groups;treatment group（42 cases）,Ganciclovir were given;control group（40 cases）,only Ribavirin were used here.Results：The outcome was better in treatment group than in the control with treatment group 97.62%and the control group 75%respectively. The difference of the two groups was statistically siginificant（P0.05）.Conclusion：A good therapeutic result can be obtained by Ganciclovir for hand-foot-mouth disease.in children.This treatment is worthwhile to be spred in order to cure the hand-foot-mouth disease.in children with better effect and higher safety.