摘要
介绍了非经典铂类抗癌配合物的发展概况,并按中心离子价态、配体及配合物结构特征对其进行分类,讨论其构效关系。
The development of nonclassical platinum antitumor complexes is introduced These complexes are classified according to the characteristics of centralion oxidation state,ligands and the structure.The structureactivity relationships are discussed indicating that there is certain instructive significance to the exploration of the novel platinum antitumor drugs.
出处
《化学研究与应用》
CAS
CSCD
1999年第3期235-240,共6页
Chemical Research and Application
基金
浙江省自然科学基金
浙江海正药业有限公司资助项目
关键词
抗癌药物
铂类
配合物
构效关系
antitumor drugs,platinum complex,structureactivity relationship,development