人工真皮修复骨外露创面23例效果评价

Repair of bone exposed wounds using artificial dermis in 23 cases

背景:近年来有应用人工真皮修复骨外露创面的报道,但其治疗效果尚不明确。目的:评价应用人工真皮修复23例骨外露创面的治疗效果。方法:选取北京积水潭医院烧伤科23例骨外露患者,男18例,女5例。骨外露创面清创后,进行人工真皮移植,待其成活后,进行自体薄断层皮片移植,观察人工真皮及自体断层皮片的成活情况和供皮区瘢痕增生情况。结果与结论:所有骨外露患者中除1例女性颅骨外露部分修复外,其余患者人工真皮及自体皮片成活良好,骨外露创面均完全修复,供皮区未见瘢痕。结果提示,人工真皮修复骨外露创面效果较好。

BACKGROUND： In recent years, artificial dermis has been reported to repair bone exposed wound, but the treatment effect remains unclear. OBJECTIVE： To evaluate the therapeutic effect of artificial dermis in repairing bone exposure in 23 cases. METHODS： A total of 23 patients with bone exposure were selected from the Department of Burns, Beijing Jishuitan Hospital, including 18 males and 5 females. Patients underwent debridement and artificial dermal transplantation, followed by split thickness autoskin transplantation. The survival of artificial dermis and split thickness autoskin was observed, as well as scar hyperplasia at the skin donor site. RESULTS AND CONCLUSION： The bone exposed wounds of 22 patients were completely recovered and scar formation were not observed at donor site after surviving of artificial dermis and split thickness autoskin, only skull exposure was partially covered in one femal patient. Artificial dermis has a good therapeutic effect in repairing bone exposure.