老龄供者亲属肾移植120例

Elderly donors in living kidney transplantation in 120 cases

背景:为了保证老龄供肾的移植效果,应当慎重选择供者。国内活体肾移植开展较晚,对老龄亲属供肾移植经验仍较欠缺。目的:对老龄供肾亲属肾移植的效果和安全性进行分析。方法:纳入120例行活体肾移植的供、受者资料进行回顾性分析,其中夫妻间供肾12例,父母供给子女75例,其他亲属供肾33例,供者55岁以上52例。比较老年供者和非老年供者移植前血清肌酐值,移植后肾功能恢复状况及并发症发病率等,同时对2组受者的移植前后血清肌酐及并发症进行比较。结果与结论:两组供者移植后肾功能恢复良好,无显著性差异;两组受者在移植后1周,1个月,1年内比较血清肌酐差异无显著性意义,急性排斥发病率差异亦无显著性意义。提示,老龄供者制定合理入选标准,对供者是安全的,受者和移植肾近期效果良好。

BACKGROUND：To assure the efficacy of elderly living kidney transplantation,we must carefully select elderly donors. The experience of elderly living kidney transplantation is insufficient due to late performance in China. OBJECTIVE：To investigate the efficacy and safety of elderly living kidney transplantation. METHODS：A retrospective analysis of 120 living kidney donors and recipients were performed. Twelve of them were husbands and wives,75 of them were parents and children,and the other 33 were relatives. Fifty-two donors were over 55 years old. The level of serum creatinine （SCr） before transplantation,kidney function recovery and complication after transplantation were compared between elderly and non-elderly donors. Meantime,the SCr levels and complications recipients were compared between two groups. RESULTS AND CONCLUSION：Their kidney functions recover well in two groups without significant differences. There were no significant differences between two groups in serum SCr levels at 1 week,1 month and 1 year after transplantation. The acute rejection had no significant difference between two groups. A reasonable select standard is safe to elderly donors. The recipients and their kidney functions recover well.