出生时轻度窒息史对出生七天后新生儿排尿方式的影响

Effect of mild asphyxiation influence on voiding in newborns

目的 探讨出生时轻度窒息对出生7d后新生儿排尿方式的影响。方法 选取出生28d内、无下尿路疾患的34例有轻度窒息病史的新生儿及33例无窒息史新生儿，其中窒息史组正常体重（ANW）16例，体重（2．83±0．31）kg，年龄（11．1±2．7）d;低体重（ALW）18例，体重（1．68±0．54）kg，年龄（14．5±7．6）d。无窒息史组正常体重（NANW）18例，体重（3．24±0．43）kg，年龄（11．8±2．2）d和低体重（NALW）15例，体重（1．88±0．32）kg，年龄（15±8．3）d。各组均进行12h（9am～9pm）自由排尿观察，记录排尿频率、每次排尿量、B超测量排尿后残余尿量、排尿时是否处于睡眠状态。结果 共记录排尿533次。ANW组排尿次数（9．5±2．7）次，明显高于NANW组（7．7±2．3）次（P〈0．05），但排尿量和残余尿量差异无统计学意义。ALW组与NALW组排尿次数、排尿量和残余尿量差异无统计学意义。ANW组排尿次数（9．5±2．7）次、排尿量（17．7±5．8）ml，明显高于ALW组（7．7±2．3）次，（13．5±6．1）ml，但残余尿量差异无统计学意义。NANW组排尿量（21．1±11．0）ml明显高于NALW组（13．1±6．2）ml（P〈0．05），但排尿次数和残余尿量差异无统计学意义。膀胱排空率和排尿时清醒百分率在ANW组和NANW组中均较高，二者差异不明显；在ALW组和NALW组中差异也不明显。结论 新生儿出生时轻度窒息史可能对正常体重儿排尿次数有明显影响；对新生儿排尿量和残余尿量影响不大。

Objective The aim of this study was to investigate the effect of mild asphyxiation （A） on voiding pattern of newborns. Methods A total of 67 newborns, 34 cases with mild asphyxiation and 33 cases normal, without low urinary tract pathological abnormalitiesdiseases, single birth, hospitalized in NICU were included in this study. They were divided into 4 groups： 16 cases of asphyxiation with normal weight（ANW）, 18 cases of asphyxiation with low weight（ALW）, 18 cases of no asphyxiation with normal weight （NANW）and 15 cases of no asphyxiation with low weight （NANW）. Each group undertook 12 hours （9.00am -9：00 pm） free voiding observation. We recorded, recording voiding time, the voiding volume, post-voiding residual urine （PVR） by B ultrasound, empty voiding and awake or sleep percentage at voiding. Results Five hundred and thirty three episodes of voiding were recorded. The voiding frequency in ANW （9. 5±2. 7）times is higher than those of NANW（7. 7＋2. 3）times （P〈0. 05）, but the voiding volume and PVR are no significant difference （P〉0. 05）between 2 groups. The voiding frequency, volume and PVR in ALW and NALW are no significant differenee（P〉0. 05）. The voiding frequency and volume in ANW（9. 5 ±2. 7）times, （17.7±5.8）ml respectively is higher than ALW（7. 7±2. 3）times, （13. 5±6. 1 ）ml （P〈0. 05）, but PVR are no significant difference（P〉0. 05）. The voiding volume in NANW （21.1 ±11.0）ml is higher than NALW（13. 1±6. 2）ml（P〈0. 05）, but the voiding frequency and PVR are no significant difference（P 〉0. 05）. Voiding empty and awake percentage is higher in ANW and NANW, but no significant difference; voiding empty and awake percentage in LNW and NALW are no significant difference. Conclusions Mild asphyxiation induced more voiding frequencies in ANW newborn but it has little impact on voiding volume, PVR, empty voiding percentage and awake voiding percentage in all newborns. Its mechanism is unclear.