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改良单克隆抗体特异性俘获血小板抗原技术的简化及其临床意义 被引量:3

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摘要 原发免疫性血小板减少症(hnmune thrombocytopenic purpura,ITP)患者体内存在的抗血小板自身抗体与自身血小板结合后介导其在单核巨噬细胞系统中被吞噬破坏,使得循环血小板数下降,导致全身广泛皮肤黏膜、甚至内脏出血。目前该病仍为排除性诊断。既往血小板相关免疫球蛋白的检测因为缺乏特异性,已经基本上没有临床鉴别诊断价值。
出处 《中华血液学杂志》 CAS CSCD 北大核心 2011年第3期206-207,共2页 Chinese Journal of Hematology
基金 国家自然科学基金(81070397、30670900) 公益性卫生行业科研专项基金(200802031) 天津市应用基础及前沿技术研究计划(09JCYBJC10900、10JCZDJC19700)
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