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Toll样受体7与哮喘的关系

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摘要 人类Toll样受体(toll-like receptors,TLRs)是近年来发现的一类信号传导跨膜受体,可以识别、结合病原体相关分子模式,启动免疫反应,是人体先天免疫和获得性免疫的桥梁.TLR7作为TLRs家族中重要的成员,在生理、病理中均起着重要的作用,维持它的正常功能对人体的健康非常重要,如Mφller-Larsen等发现TLR7和TLR8两个受体在支气管哮喘中有着重要的作用机制.本文着重对TLR7在生理和病理中的作用并与哮喘的关系,参考国内国外的文献最新进展作一综述.
出处 《中国医师杂志》 CAS 2011年第2期283-285,共3页 Journal of Chinese Physician
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