经肝铁浓度测定证实的血色病2例
被引量:3
Two special cases with hemochromatosis confirmed by hepatic iron determination
摘要
2007年,中南大学湘雅二医院建立肝铁浓度测定方法,至今已测定370例患者,发现6例肝铁浓度〉5000μg/g(肝组织干重),其中2例〉15000μg/g,对此2例进行了系统的检查,确诊为血色病,报道如下。
出处
《中华肝脏病杂志》
CAS
CSCD
北大核心
2011年第3期226-227,共2页
Chinese Journal of Hepatology
关键词
血色素沉着症
贫血
铁粒幼细胞
肝铁浓度
Hemochromatosis
Anemia, sideroblastic
Hepatic iron concentration
二级参考文献86
-
1[1]Feder JN,Gnirke A,Thomas W,Tsuchihashi Z,Ruddy DA,Basava A,Dormishian F,Domingo R Jr,Ellis MC,Fullan A,Hinton LM,Jones NL,Kimmel BE,Kronmal GS,Lauer P,Lee VK,Loeb DB,Mapa FA,McClelland E,Meyer NC,Mintier GA,Moeller N,Moore T,Morikang E,Prass CE,Quintana L,Starnes SM,Schatzman RC,Brunke KJ,Drayna DT,Risch NJ,Bacon BR,Wolff RK.A novel MHC class Ⅰ-like gene is mutated in patients with hereditary haemochromatosis.Nat Genet 1996;13:399-408
-
2[2]Merryweather-Clarke AT,Pointon JJ,Shearman JD,Robson KJ.Global prevalence of putative haemochromatosis mutations.J Med Genet 1997; 34:275-278
-
3[3]Piperno A,Sampietro M,Pietrangelo A,Arosio C,Lupica L,Montosi G,Vergani A,Fraquelli M,Girelli D,Pasquero P,Roetto A,Gasparini P,Fargion S,Conte D,Camaschella C.Heterogeneity of hemochromatosis in Italy.Gastroenterology 1998; 114:996-1002
-
4[4]Hayashi H,Wakusawa S,Motonishi S,Miyamoto K,Okada H,Inagaki Y,Ikeda T.Genetic background of primary iron overload syndromes in Japan.Intern Med 2006; 45:1107-1111
-
5[5]Roetto A,Papanikolaou G,Politou M,Alberti F,Girelli D,Christakis J,Loukopoulos D,Camaschella C.Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis.Nat Genet 2003; 33:21-22
-
6[6]Papanikolaou G,Samuels ME,Ludwig EH,MacDonald ML,Franchini PL,Dube MP,Andres L,MacFarlane J,Sakellaropoulos N,Politou M,Nemeth E,Thompson J,Risler JK,Zaborowska C,Babakaiff R,Radomski CC,Pape TD,Davidas O,Christakis J,Brissot P,Lockitch G,Ganz T,Hayden MR,Goldberg YP.Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis.Nat Genet 2004; 36:77-82
-
7[7]Camaschella C,Roetto A,Cali A,De Gobbi M,Garozzo G,Carella M,Majorano N,Totaro A,Gasparini P.The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.Nat Genet 2000; 25:14-15
-
8[8]Montosi G,Donovan A,Totaro A,Garuti C,Pignatti E,Cassanelli S,Trenor CC,Gasparini P,Andrews NC,Pietrangelo A.Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene.J Clin Invest 2001; 108:619-623
-
9[9]Njajou OT,Vaessen N,Joosse M,Berghuis B,van Dongen JW,Breuning MH,Snijders PJ,Rutten WP,Sandkuijl LA,Oostra BA,van Duijn CM,Heutink P.A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis.Nat Genet 2001; 28:213-214
-
10[10]Lamon JM,Marynick SP,Roseblatt R,Donnelly S.Idiopathic hemochromatosis in a young female.A case study and review of the syndrome in young people.Gastroenterology 1979; 76:178-183
同被引文献8
-
1Konstantinos Tziomalos,Vassilios Perifanis.Liver iron content determination by magnetic resonance imaging[J].World Journal of Gastroenterology,2010,16(13):1587-1597. 被引量:16
-
2吴煜,李跃旗.慢性丙型病毒性肝炎与铁代谢异常[J].传染病信息,2006,19(4):178-181. 被引量:1
-
3NrederauC,FrieherR,SonnenbergA,eta1.SurvivalandcausesofdeathincirrhoticandinnoncirrhoticpatientswithprimaryhemochromatosisfJ].N.EnglNed,1985,313(20):1256-1262.
-
4Rouault TA. Hereditary hemochromatosis. JAMA, 1993, 269: 3152- 3154.
-
5Fargion S, Fracanzani AL, Piperno A, et al. Prognostic factors for hepatocellular carcinoma in genetic hemochromatosis. Hepatology, 1994, 20: 1426-1431.
-
6李丽,贾继东,王宝恩.血色病的欧美诊断治疗规范[J].胃肠病学和肝病学杂志,2008,17(1):1-3. 被引量:29
-
7王同显,马保风(综述).慢性输血性铁超负荷[J].国际输血及血液学杂志,2010,33(2):168-171. 被引量:2
-
8李爱华,黄金明,孔祥泉,叶进,侯晓华.1个遗传性血色病家系的临床MRI诊断[J].临床肝胆病杂志,2011,27(3):302-305. 被引量:5
引证文献3
-
1岳丽娟.慢性丙型肝炎合并血色病1例[J].中国当代医药,2012,19(5):142-142. 被引量:1
-
2张国强,夏敏,郭继中,姚选军,杨树东.不典型原发性血色病1例[J].中华肝脏病杂志,2012,20(8):630-631. 被引量:1
-
3赵文学,刘拉羊,纪泛扑,陈明霞,翟嵩,王芳侠,邓红.血色病患者临床表现及病理学特征分析[J].西部医学,2013,25(10):1476-1479. 被引量:2
二级引证文献4
-
1毕宝林,李世华,苏延峰,田昭涛,仲薇薇,李金辉.血清铁蛋白对军团菌肺炎的临床诊断价值[J].西部医学,2015,27(1):63-65.
-
2万小坤,李杰,梅列军.血色病影像学表现及病理学特征[J].武汉大学学报(医学版),2015,36(4):584-587. 被引量:2
-
3王俊,刘飞.血色病并Dubin-Johnson综合征一例误诊讨论[J].临床误诊误治,2016,29(9):41-42. 被引量:1
-
4杨倩,查兵兵,李芸菲,丁和远,刘军.无铜蓝蛋白血症合并抗利尿激素分泌失调综合征1例报告[J].中国实用内科杂志,2024,44(8):698-701.
-
1曾茂法.比色法测定枸橼酸铁铵制剂中铁的含量[J].中国药品标准,2006,7(3):31-33. 被引量:3
-
2第四届全国治疗药物监测学术年会在长沙召开[J].中南药学,2014,12(9).
-
3陈敏,谢吉民,程晓农,荆俊杰.镉对小鼠肝脏的毒作用机理探讨[J].江苏大学学报(医学版),2002,12(4):321-323. 被引量:20
-
4李琳,张志华,吴建梁,靳峥.脑脊液高浓度铁诱导大鼠阿尔茨海默病样行为学和病理学的特征性变化[J].医药导报,2005,24(4):272-275. 被引量:1
-
5体内含铁过多可致病[J].健康人生,2005(5):24-24.
-
6陈敏,程晓农,谢吉民,高晓钦,荆俊杰.镉对小鼠体内钙、铁稳态的影响[J].江苏理工大学学报(自然科学版),2000,21(3):67-69. 被引量:10
-
7邱相君,路西明,李艳,代宗顺.右旋糖酐铁分散片的人体生物等效性研究[J].现代中西医结合杂志,2005,14(21):2784-2786. 被引量:1
-
8王敏,肖青,李香铃,王延娟,马传香,王金铃.大剂量重组人促红细胞生成素对肾性贫血患者骨髓象及铁代谢的研究[J].潍坊医学院学报,2005,27(2):86-89. 被引量:2
-
9胡长梅,霍继荣,彭捷.泮托拉唑与奥美拉唑对消化性溃疡致上消化道出血的疗效比较[J].中国药业,2005,14(3):61-62. 被引量:15
-
10陈海滨,吴蔚,李文珠,冷爱民.抗肝纤维化化学药研究概况[J].中国药房,2008,19(13):1021-1023. 被引量:3