图形视觉诱发电位振幅与峰潜伏时比值对开角型青光眼早期诊断价值

Significance of relative value of amplitude/latency of pattern visual evoked potentials in early diagnosis of Open angle glaucoma

目的探讨图形视觉诱发电位（PVEP）的振幅／峰潜伏时（A／LT）比值在开角型青光眼（POAG）早期诊断中的应用。方法检测可疑开角型青光眼56例（84只眼）、早期POAG患者62例（90只眼）及正常对照组40例（80只眼）PVEP及A／LT比值。结果可疑POAG及早期POAG患者PVEP检测阳性率均高于正常对照组，可疑POAG及早期POAG患者PVEP检测阳性率之间差异无统计学意义。可疑POAG及早期POAG患者A／LT比值分别为1．16和1．29，两者差异有统计学意义。结论PVEP的A／LT比值分析在POAG早期诊断中有较好地临床应用前景。

Objective To study the primary open angle glaucoma by relative value of amplitude/latency through pattern visual evoked potential examination （PVEP） for early diagnosis. Methods Fifty-six cases （84 eyes） doubtful primary open angle glaucoma, 62 cases （90 eyes） of early primary open angle glaucoma and 40 cases （80 eyes） of normal controls were tested for relative value of amplitude/latency. Results The abnor mal ratio of doubtful and early primary open angle glaucoma was higher than that in normal controls. The abnormal ratio of doubtful and early primary open angle glaucoma was different, which was insignificant. Relative value of amplitude/latency in doubtful and early primary open angle glaucoma were 1.16 and 1.29, the difference was statistically significant （P〈0.05）. Conclusion Relative value of amplitude/latency has a better perspective of clinical application in early diagnosing open angle glaucoma.