呼吸中枢化学反应性、发作性睡病与HLA-DQBl*0602基因
被引量:1
摘要
呼吸中枢低氧反应性的高低受遗传的调控,尽管动物实验发现了多个候选基因,但目前尚未见人体相关基因的报告。发作性睡病(narcolepsy)是一种少见睡眠疾病,以难以控制的嗜睡、发作性猝倒、睡瘫、入睡幻觉及夜间睡眠紊乱为主要临床特点,超过95%的典型患者存在人类白细胞抗原(HLA)DQBl*0602基因阳性、脑脊液下丘脑分泌素降低或消失等表现。
出处
《中华结核和呼吸杂志》
CAS
CSCD
北大核心
2011年第3期186-186,共1页
Chinese Journal of Tuberculosis and Respiratory Diseases
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