原发性卵巢类癌病例报告及文献复习

Primary ovarian carcinoid:a report of case and review of literature

目的:探讨原发性卵巢类癌组织起源,临床病理特点、治疗及预后。方法:报道2例原发性卵巢类癌,并进行临床病理分析。结果:病例1中患者为40岁女性,病例2中患者为33岁女性,2例患者临床症状均有下腹疼痛,2例患者均接受手术治疗。组织病理学类型为:岛状型。临床病理分期病例1为Ⅰa期,手术后无其他治疗已无瘤生存9年;病例2为Ⅲc期,术后接受化疗,6个月后死于本病。结论:原发性卵巢类癌是一种罕见的低度恶性肿瘤,无典型临床症状,诊断需除外转移性类癌。早期患者行单纯手术治疗后愈后良好,晚期患者愈后差,化疗不敏感。

Objective：To explore the genesis,clinicopathological features,treatment and prognostic of primary ovarian carcinoid.Methods： Two primary ovarian carcinoid cases treated in our hospital are reported and analyzed in terms of clinicopathology.Results： Case 1 was a 40-year-old woman and case 2 was a 33-year-old woman.Both of them,with hypogastralgia as main complaint,had no other clinical complications.Surgeries were performed on both cases.The histological type of these two cases was insular type.Case 1 was staged as Ⅰa and case 2 staged as Ⅲc according to postoperative pathology.Case 1 received no postoperative therapy,and had kept alive with no evidence of tumour for 9 years.Case 2 received additional chemotherapy and ended up with death 6 months after operation.Conclusion： Upon literature review,primary ovarian carcinoid is an extremely rare ovarian tumor with low potential of malignancy.It has no typical clinical symptoms and should be differentiated from metastatic ovarian carcinoid.Surgery is the most proper treatment for primary ovarian carcinoid of early stage.A case of advanced stage has a bad prognosis and chemotherapy is inefficient.