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脑胶质瘤患者血清骨桥蛋白水平的测定及其临床意义 被引量:4

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摘要 骨桥蛋白(osteopontin,OPN)是一种分泌性磷酸化糖蛋白,可起到促进细胞趋化、黏附、迁移和增殖等多种作用,与肿瘤的发生发展关系密切.
出处 《中华外科杂志》 CAS CSCD 北大核心 2011年第2期174-175,共2页 Chinese Journal of Surgery
基金 山东省自然科学基金资助项目(Y2007C108)
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  • 1杨晓清,滕良珠.脑膜瘤增殖与复发的分子生物学机制研究进展[J].山东医药,2006,46(30):76-77. 被引量:2
  • 2曾涛,陈衔城,宫晔,秦智勇,张义.骨桥蛋白在脑动静脉畸形栓塞治疗中的意义[J].中华外科杂志,2007,45(12):849-851. 被引量:1
  • 3曾涛,杨卫忠,石松生,张国良,王春华.骨桥蛋白在中枢神经系统中多种恶性肿瘤的表达[J].中国临床神经科学,2007,15(5):455-458. 被引量:2
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  • 8Chakraborty G, Jain S,Kundu GC.Osteopontin promotes vascular endothelial growth factor-dependent breast tumor growth and angiogenesis via autocrine and paracrine mechanisms [ J ].Cancer Res, 2008,68 ( 1 ): 152-161.
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  • 10Chen YJ ,Wei YY, Chen HT et al.Osteopotin increases mi- gration and MMP-9 up-regualstion viactv133 integrin,FAK, ERK,and NF-r,B-dependent pathway in hunman chondro- sarcoma cells [J].J Cell, Physiol, 2009,221 ( 1 ):98-108.

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