平消胶囊联合DP方案同步放化疗治疗中晚期宫颈癌84例的临床分析

Clinical evaluation of Pingxiao Capsule combined with DP chemotherapy plus radiotherapy for advanced cervical cancer

目的:评价平消胶囊联合DP方案同步放化疗治疗中晚期宫颈癌的临床疗效及不良反应。方法:将84例中晚期宫颈癌患者随机分成两组,实验组42例应用平消胶囊联合同步放化疗,对照组42例行单纯同步放化疗。结果:实验组和对照组近期有效率分别为95.2%和92.9%,两组差异无统计学意义;生活质量改善率分别为85.7%和47.6%;主要的不良反应是骨髓抑制,白细胞下降率分别是54.8%和95.2%,有明显统计学差异。结论:平消胶囊联合同步放化疗虽未提高近期有效率,但是可以降低骨髓抑制的发生,提高患者生存质量。

Objective：To evaluate the efficacy and toxicity of Pingxiao Capsule combined with DP chemotherapy plus radiotherapy for advanced cervical cancer.Methods： A total of 84 patients with advanced cervical cancer were randomized into two groups.The treated group was treated with Pingxiao Capsule and chemotherapy plus radiotherapy,the control group was treated with chemotherapy plus radiotherapy.Results： The effective rates（CR＋PR）of the two groups were 95.2% and 92.9%;the improved rates of quality of life（QUL）were 85.7% and 47.6% respectively.The main toxicities were leukopenia（54.8% and 95.2%）.Conclusion： Although,Pingxiao Capsule combined with DP chemotherapy plus radiotherapy for advanced cervical cancer could not increase the short term effect,but which could decrease the occurrence of myelosuppression and improve QOL.