广西壮族自治区居民重性抑郁症流行病学调查

Prevalence of major depression disorders in urban and rural residents of Guangxi Zhuang Autonomous Region,China

目的了解广西壮族自治区居民重性抑郁症的患病水平和分布特征。方法采用多阶段分层整群随机抽样方法抽取广西壮族自治区6个地级市和10个县≥15岁常住居民共21 290人,采用复合性国际诊断问卷3.0版(CIDI 3.0)和自编调查表进行面访调查,并采用国际疾病及相关健康问题分类第10版(ICD-10)进行诊断。结果重性抑郁症时点患病率和终生患病率分别为3.40‰和5.32‰;女性重性抑郁症的时点患病率高于男性(P<0.05);其他民族时点患病率高于汉族和壮族居民(P<0.01);时点患病率的患病年龄主要为55～64岁(P<0.05);离婚人群重性抑郁症的时点患病率和终生患病率均较高(P<0.01)。结论广西壮族自治区居民重性抑郁症患病率较高,女性、年龄55～64岁、离婚的居民是预防重性抑郁症的重点人群。

Objective To investigate the prevalence and distribution of major depression disorders among people aged ≥15 years in urban and rural areas of Guangxi Zhuang Autonomous Region. Methods From July through December,2007,21 290 subjects aged ≥15 years were randomly selected with stratified multi-stage cluster sampling method.All subjects were investigated with a face-to-face interview.The Composite International Diagnostic Interview（CIDI 3.0）was used as the screening tool and the diagnoses were made with the 10th edition of International Classfication of Disease Criteria. Results The current prevalence of major depression disorders was 4.32‰ in the female and 2.50‰ in the male with a significant difference（P0.05）.The lifetime prevalence of major depression disorders was 5.98‰ in the female and 4.68‰ in the male.The lifetime prevalence of major depression disorders was different in adullts of different age（P0.05）.There was a statistically significant difference（P0.05）in the current prevalence of major depression disorders between different age groups with a current prevalence peaks in the adults at age of 55-64 years.There were differences in the current and lifetime prevalence of major depression between adults with different marital status（P0.05） with higher current and lifetime prevalences among the adults divorced. Conclusion Major depression disorder is prevalent among urban and rural adult residents in Guangxi and correlates to some socio-demographic factors.