妊娠合并原发性血小板减少性紫癜(附35例分析)

Pregnancy Complicated with Idiopathic Thrombocytopenic Purpura(Analysis of 35 Cases)

本文分析我院1980年1月～1988年12月间35例妊娠合并原发性血小板减少性紫癜的临床资料.本组以血小板≤50×10~9/L 为诊断标准,其发生率为0.16%。35例中17例行骨髓穿刺,27例以肾上腺皮质激素治疗。本文围产儿病死率14.3%(5/35),5例围产儿死亡为3例死胎和2例新生儿死亡;产后出血发生率为11.43%(4/35),但无母亲死亡。文章对孕期、分娩期和新生儿的处理进行了讨论。

The clinical data of 35 cases of Pregnancy with Idiopathic ThrombocytopenicPurpura (ITP) in this hospital from January, 1980 to December, 1988 were analyzed.The diagnosis of ITP in this series was established by the criteria of platelet countless than 50×110^(?)/L. The incidence was 0.16%. Of the 35 cases 17 (48.57%) pregnan-cies bone marrow aspirate were performed and 27 pregnant woman were treated withadrenal corticosteroids. Fetal death was as follows: stillbirth, 3; death of newbornchild, 2, and the fetal mortality rate was 14.3%(5/35). The incidence of postpartumhemorrhage was 11.43%(4/35) but there was no maternal death in this series. Final-ly, managements during pregnancy, at the delivery and for the newborn childrenwere discussed.