PET与脑科学

脑显像是PET技术在人体脏器显像上最早应用，也是临床及基础医学研究的一个重要领域［1］IPET脑显像条件实现PET脑显像必须具备两个基本条件：显像设备和显像药物。前者主要是PET扫描仪；后者为各种发射正电子核素标记的脑显像剂，其制备需要回旋加速器及自动化学合成装置...

Positron emission Tomography (PET) is one of the modem medical imaging techniquesand plays a powerful role in the study on the human brain, including normal state and many brain diseases.18F-FDG PET has been most widely used in basic research and clinical neurology, such as human braindevelopment and aging, localization of cerebral functional area,diagnosis and management of brain tumor,epilepsy and Alzheimer's disease. Neuroreceptor imaging is the characteristic approach of brain PET andhas been successfully applied to the study of brain aging, neuron activity, Parkinson's disease, psychiatric diseases and drug development. The evaluation of cerebral blood flow with H215O and oxygen metabolism with 13O steady-state method is also an important aspect in the study of brain function andcerebrovascular diseases.