超微提取当归阿魏酸工艺研究

Study on Ultrafine Extraction Technology of Effective Ingredients in Angelica Sinensis

目的:比较当归超微提取和常规提取工艺,并优化超微提取工艺,解决超微提取过程中遇到的问题。方法:采用正交试验法,对提取时间、提取温度、提取溶剂和提取料液比4个因素进行优化,确定最优工艺。结果:超微提取的最优工艺为料液比1:20,提取时间1h,溶剂的浓度70%,提取温度90℃,比常规提取可缩短1/2时间。结论:超微提取能明显节约时间,且提取率可高出40%左右,节约了成本,如能解决提取中的一些问题,工业化前景将更为广阔。

Objective：To explore the difference of ultrafine extraction technology and conventional extraction technology on angelica sinensis,optimize the best ultrafine extraction technology,resolve the problems in the process of ultrafine extraction.Methods：Using Orthogonal experiment to choice extraction times,extraction temperature,solvent concentration,solvent amount,to ascertain optimization.Results：The best condition of the angelica chinensis was with 70 % ethanol of 20 folds volume,one hour in 90℃,Comparing with conventional extraction technology,extraction time is 1/2 of general methods.Conclusion：Ultrafine extraction technology can reduce the extracting time,improved 40% the extracting rate of effective constituents,save the cost price of manufacture,if we could solve some problems on extraction,the technology can be used in pharmacy enterprises.