河南汉族大学生群体苯硫脲尝味能力调查

Investigation of the phenylthiocarbamide-taste sensitivity in students of Henan Han population

目的调查河南汉族大学生群体苯硫脲(PTC)味盲基因频率的分布情况。方法采用阈值法研究新乡医学院2006级和2007级1 009名在校大学生的尝味能力,并计算味盲率。结果 1 009名在校大学生的味盲率为13.08%,味盲基因频率为36.30%。男、女生味盲率分别为13.68%和12.69%,二者比较差别无统计学意义(P>0.05)。结论河南汉族大学生群体味盲率与中国其他省汉族人群味盲率一致,且PTC尝味能力的分布与性别无关。

Objective To investigate the distribution of phenylthiocarbamide（PTC）-taste blindness in the students of Henan Han population.Methods The PTC-taste sensitivity of 1 009 students from Grade 2006 and Grade 2007 in Xinxiang medical college was detected by threshold method,allelic and genotype frequencies of PTC-taste blindness were calculated by statistics method.Results The phenotype frequency of PTC-taste blindness in the students was 13.08%,and allelic frequency of PTC-taste blindness was 36.30%.The phenotype frequencies of PTC-taste blindness in male and female students were 13.68% and 12.69% respectively,and there was no significant difference on the distribution of PTC-taste blindness between males and females（P〉0.05）.Conclusion Frequency of PTC-taste blindness in Henan Han population was accord with other Han population in China.There is no gender difference on distribution of the PTC-taste sensitivity.