LASEK联合丝裂霉素C矫正较高曲率近视

The clinical observation of LASEK combined with mitomycin C to correct the higher curvature myopia.

目的观察准分子激光角膜上皮瓣下磨镶术（LASEK）联合丝裂霉素C（MMC）矫正较高曲率近视的临床效果和安全性。方法应用美国雷赛公司LSX5．2准分子设备对52例（99眼）曲率较高的近视（角膜曲率大于46D）施行LASEK联合0．02％的MMC治疗。观察术后症状、裸眼视力、显然屈光度、眼压、角膜地形图及角膜上皮下雾状浑浊（haze）出现情况。结果术后5d内角膜上皮基本愈合。裸眼视力与屈光度均存术后6个月内趋于稳定。其中92眼（92．93％）等于或优于术前最佳矫正视力屈光度平均为（＋0，11±0．75）D。角膜地形图检查图形对称性良好，无明显偏心切削或不规则切削。术后有7眼（7．07％）出现haze，按照Fantes（1990）分级标准≤2级，无其他术后严重并发症。结论LASEK联合MMC矫正较高曲率近视有良好的效果。

Objective To observ the clinical efficacy and safety of laser-assisted subepithelial keratiomilensis （LASEK） combined with mitomycin C （MMC） in the treatment of the higher curvature myopia. Methods 52 cases （99 eyes） of higher curvature myopia were treated by LASEK. United States Raiser＇ s LSX5.2 excimer equipmet was applied combined with 0. 02% mitomyein C. The corneal curvature was above 46 D in all of the eyes. Postoperative symptoms, uncorrected visual acuity （UCVA） , refraction, intraocular pressure, corneal topography, and haze occurrence were observed. Results the corneal epithlium were basic healed in 5 days after operation. The uneorreeted visual acuity and refraction were stable in 6 months after operation. There were 92 eyes （92.93%） got a UCVA no less than preoperation best corrected visual acuity, The average refraction was ＋ 0. 11 ± 0. 75 D. According to the corneal topography examination, graphic symmetry was good, and no obvious bias cutting and irregular cutting. Haze occurred in 7 eyes （7.07%） after operation, it was ≤2 grade accordance with the Fantes （1990） grading standards. No serious complications appeared. Conclusion The treatment of the higher curvature myopia with LASEK combined with mitomycin C have a good outcome.