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低潮气量联合个体化呼气末正压用于胸科手术患者单肺通气效果观察 被引量:4

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摘要 目的比较低潮气量联合个体化呼气末正压(PEEP)单肺通气(OLV)与常规OLV的通气效果。方法选择44例全麻行食管癌根治术患者随机分为联合组和常规组各22例,两组均先行双肺通气(TLV)30 min,后改行OLV。联合组OLV时潮气量(VT)为6~8 ml/kg,根据动态压力—容积(P-V)曲线目测其呼气支上拐点(最大曲率点,PMC)对应的压力PPMC设置PEEP。常规组为VT 10 ml/kg,PEEP为0。于TLV 30 min(T1)、OLV 30 min(T2)和气管拔管后30 min(T3)时分别记录气道峰压(Peak)、气道阻力(Raw)、胸肺顺应性(CT)和呼气末二氧化碳分压(PETCO2)、平均动脉压(MAP)、心率(HR);并在各时点采集动脉血和中心静脉血标本行血气分析(pH、PaO2、PaCO2);计算肺内分流率(Qs/Qt)。结果与T1相比,两组T2时HR、Peak、Raw、Qs/Qt均升高,CT、PaO2均降低;与常规组比较,联合组T2时Peak、Raw、Qs/Qt降低,PaO2、CT增加;T3时PaO2增高,Qs/Qt降低,P均<0.05。结论全麻OLV期间选择6~8 ml/kg潮气量联合PPMC水平的PEEP可明显改善动脉氧合,是临床个体化保护性OLV的理想通气方式。
出处 《山东医药》 CAS 北大核心 2011年第11期90-91,共2页 Shandong Medical Journal
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同被引文献27

  • 1吴荣信,丁雄,吉俭,郑忠欣,黎南中,陈卫东.不同单肺通气模式与动脉血氧分压关系的实验与临床研究[J].华南国防医学杂志,2000,14(2):29-31. 被引量:2
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