肝脏局灶结节性增生MRI表现与病理对照研究

Controlled study on MRI manifestation and pathology of liver focal nodular hyperplasia

目的:探讨肝脏局灶结节性增生(FNH)的MRI表现,并与病理进行对照研究。方法:回顾性分析16例经手术病理证实的肝脏FNH的MRI表现。结果:16例病变均为单发。平扫13个病灶在T_1WI呈低或稍低信号,T_2WI呈等或稍高信号,3个呈等信号,其中5个病灶中央瘢痕区呈更长T_1更长T_2信号影。动态增强扫描,动脉期13个病变均呈明显强化,门脉期5个病灶呈稍高信号,11个病变呈等或稍低信号,其中2个病变中央更低信号区稍强化;延迟期7个病灶近等信号,9个病灶呈略低信号,而病灶中央更低信号区仅3例呈高信号明显强化。结论:FNH是一种良性病变,有时术前不易确诊,典型的MRI表现结合临床表现能够对肝脏FNH进行定性诊断。

Objective： To investigate the MR imaging features of the liver focal nodular hyperplasia（FNH） and proceed a controlled research with pathohistologic findings. Methods： MRI manifestations of liver FNH in 16 cases confirmed by surgery and pathology were analyzed retrospectively. Results： Sixteen cases were all single lesions. MR plain scan： 13 lesions showed low or little slight lower signal in T1 WI, equal or little slight higher signals in T2 WI, the other 3 lesions showed equal signals; 5 of the 16 lesions showed longer T2 and T1 signal in central scar area. Dynamic contrast-enhanced scan： 13 lesions were obviously enhanced in arterial phase, 5 lesions showed slight higher signals, 11 lesions showed equal or little lower signals in portal venous phase, the more hypointensity areas in 2 lesions of which showed little intensified in their center. In delayed phase, there were 7 equal signals and 9 low signals, and only 3 lesions of which showed high signals in the center more hypointensity areas. Conclusion： FNH is a kind of benign lesion, and it is hard to diagnose lesion before the operation. The combination of typical clinical manifestations and MRI manifestations can make a qualitative diagnosis of the liver FHN.