亚氨基二乙酸盐酸盐的合成研究

Synthesis of HClSalt of Iminodiacetic Acid

研究了以氯乙酸为原料氨解合成亚氨基二乙酸盐酸盐的优化反应条件，提出了产物含量分析方法。物料摩尔比ｒ（ＣｌＣＨ２ＣＯＯＨ∶ＮＨ３∶Ｃａ（ＯＨ）２∶ＨＣｌ）＝１．０∶０．９∶１．０∶２．４；加料、反应、酸化、结晶的操作温度分别为２０～３０℃，（４５±２）℃，６０～８０℃，（０±２）℃；控制时间分别是４ｈ，６ｈ，０．５～１．０ｈ，８ｈ；所加入的氨和氯乙酸的质量分数分别为２５％和８０％。分析测定的变动系数为０．０３４％，添加回收率为９９．７２％。

The optimum conditions were studied under which chloroacetic acid was aminolysed to synthesize HClsalt of iminodiacetic acid in the presence of calcium hydroxide. The analysis method of the content of product was also proposed. The mole ratio of chloroacetic acid to ammonia, calcium hydroxide and hydrochlorid was 1.00.91.02.4. The temperatures for the operations relating to adding materials, reacting, acidifying and crystalizing were 2030 , (452) , 6580 and (02) , respectively. The time relating to these operations was 4 h,6 h, 0.51 h and 8 h, respectively. The mass fractions of ammonia and chloroacetic acid were 25% and 80%, respectively. The coefficient of variation of the analysis method was 0.034%, and the recovery rate of the addition method was 99.72%.