经尿道前列腺切除术切除前列腺组织质量及比例的影响因素分析

Evaluation of impact factors on weight and proportion of prostate tissue resected by transurethralresection of prostate

目的探讨影响经尿道前列腺切除术（TURP）切除的前列腺组织质量及比例的临床相关因素。方法收集2007年1月至2009年6月接受TURP并术后病理证实为BPH的患者458例，分析术前临床指标与TURP中切除前列腺质量、前列腺切除比例之间的相关性。结果458例患者平均年龄69．5岁，体质指数24．3kg／m2，前列腺特异性抗原（PSA）6．1μg／L，前列腺测量体积85．5ml，最大尿流率8．4ml／s，残余尿量31．8ml，前列腺切除质量32．9g，前列腺切除率37．6％。前列腺体积、体质指数与前列腺切除体积呈正相关，体质指数与前列腺切除比例正相关，前列腺体积与前列腺切除比例无相关，但前列腺体积〈40ml与〉40m1患者的前列腺切除率差异有统计学意义。非那雄胺对前列腺切除质量、前列腺切除比例无明显影响。结论前列腺体积、PSA和体质指数与TuRP切除前列腺组织质量正相关。TURP切除前列腺组织的比例与体质指数正相关，前列腺体积〈40ml的切除比例较高；非那雄胺对前列腺切除质量及比例无影响。

Objective To evaluate the impact factors on weight and proportion of prostate tissue resected by transurethral resection of prostate （TURP） in patients with benign prostatic hyperplasia （BPH）. Methods The patients undergoing TURP from January 2007 to June 2009 and diagnosed as BPH according to postoperative pathological results were enrolled in this study. The prostate volume measured by transrectal ultrasound （TRUS）, prostate specific antigen （PSA）, maximum flow rate （MFR）, residual urine volume and body mass index （BMI） were measured and calculated. The prostate tissue collected at resection was weighed, and the proportion of the prostate resected was the percentage of the pre-operative estimated weight. Results For the 458 patients with the average age of 69.5 years, average BMI was 24.3 kg/m2 , PSA 6.1μg/ml, prostate volume 85.5 ml, MFR 8.4 ml/s, residual urine volume 31.8 ml, resected prostate weight 32.9 g, proportion of resection 37.6% Prostate volume and BMI were positively related with resected prostate weight. BMI was positively related with proportion of prostate resection.There was no linear correlation between prostate volume and resected proportion. But there was significant difference in resected proportion between patients with prostate volume more than and less than 40 ml. Finasteride had no influence on the weight and resected proportion. Conclusions Prostate volume, PSA and BMI are correlated with weight and proportion of prostate tissue resected by TURP. Finasteride has no influence on the resected weight and proportion.