高强度聚焦超声肿瘤治疗技术原理

Mechanism of high intensity focused ultrasound thermal ablation therapy

高强度聚焦超声波（high—intensity focused ultrasound，HIFU）是利用超声波良好的方向性、可穿透性、生物组织吸声特性等，将体外超声换能器发射的低声强超声波准确聚焦于体内的肿瘤靶组织处。聚焦后局部组织所吸声能转化为热能可使组织瞬间升温至蛋白变性闽值温度（60℃以上）。该技术可使肿瘤细胞发生不可逆凝固性坏死，但不伤及焦点周闹正常组织。

High intensity focused ultrasound （HIFU） is a novel physical tumor therapeutic technology which applies the uhrasound well targeting, focusing, tissue absorbing property, and so on. It focused outer transducer low intensity ultrasound wave and targeted in the tumor, which can raise the temperature above 60℃ rapidly and induce tissue irreversible coagulation necrosis, with no damage to the surrounding normal tissue. It is a new physical tumor treatment technology.