摘要
肺癌血清肿瘤标志物在肺癌的早期诊断、病理分型、疾病分期、疗效评估和指导预后等方面起着重要的作用,本文旨在对神经元特异性烯醇化酶(NSE)、胃泌素释放肽(ProGRP)、细胞角蛋白19片段(CYFRA21-1)、组织多肽抗原(TPA)、鳞状细胞癌相关抗原(SCC-Ag)和癌胚抗原(CEA)这6种重要的肺癌血清肿瘤标志物的临床意义进行综述。
Lung cancer shows a tendency of higher incidence and higher mortality in recent years,but the overall 5-year survival rate is less than 15%.Serum tumor markers of lung cancer play an important role in early diagnosis,determining of pathology types,staging,evaluation of response,and prognosis of lung cancer.In this review,6 most important markers were reviewed,including neuron-specific enolase（NSE）,pro-gastrin-releasing peptide（ProGRP）,cytokeratin 19 fragments（Cyfra 21-1） ,tissue polypeptide antigen（TPA）,squamous cell carcinoma associated antigen（SCC-Ag）,carcinoembryonic antigen（CEA）.
出处
《中国肺癌杂志》
CAS
2011年第3期286-291,共6页
Chinese Journal of Lung Cancer
关键词
肺肿瘤
肿瘤标志物
诊断
治疗
Lung neoplasms
Biological tumor marker
Diagnosis
Treatment
