青年与老年食管癌的临床对比分析

Comparative Analyses of Clinical Data of Esophageal Carcinoma Between the Young and the Elderly Patients

目的探讨青年与老年食管癌患者的临床病理特点及预后差异。方法回顾性分析38例青年和44例老年食管癌患者的临床病理资料,进行对比分析。结果青、老年组患者性别比差异有统计学意义(P<0.05)。青、老年组患者术后并发症发生率差异有统计学意义(P<0.05)。青、老年组3、5年生存率差异无统计学意义(P>0.05)。青、老年组Ⅲ期患者的3年生存率差异有统计学意义(P<0.05)。Cox多因素分析显示,肿瘤TNM分期是影响全部患者预后的独立因素(P<0.05)。结论青年食管癌患者发病无性别差异,老年食管癌患者多见于男性;老年食管癌患者术后并发症较青年患者多,需要加强围术期治疗,积极防治呼吸系统并发症;早期诊疗是提高食管癌总体生存率的关键。

Objective To compare the clinicopathologic characteristics and prognoses of esophageal carcinoma between the young and the elderly patients.Methods The clinicopathologic data of 38 young patients and 44 elderly patients were compared.Results The constituent ratio of gender between the young and the elderly group was significantly different（P0.05）.The overall 3-and 5-year survival rates between the young and elderly group were not significantly different（P0.05）.The 3-year survival rate with stage Ⅲ between the young and the elderly group was significantly different（P0.05）.Cox regression showed that TNM stage was independent prognostic factor.Conclusion The incidence of young patients has no gender differences in esophageal carcinoma,but esophageal carcinoma in old patients often arises at male.Prevention and cure of complications of respiratory system are crucial to the elderly patients.The key to improve prognoses of esophageal carcinoma is early diagnosis and treatment.