脑电双频指数监测对指导心脏手术麻醉中丙泊酚用量的作用

Effects of bispectral index monitoring on guiding cardiac surgery anesthesia with Propofol drug dosage

目的：评价脑电双频指数（BIS）监测麻醉深度以指导麻醉用药在心脏手术麻醉中的应用。方法：30例择期风心瓣膜病行瓣膜置换术手术患者,随机分为两组,每组15例。对照组根据经验以微量泵连续泵注丙泊酚维持麻醉镇静深度;BIS组以微量泵连续注射丙泊酚维持麻醉镇静深度,并且根据监护仪监测的BIS值调整注射丙泊酚的速度来维持麻醉深度,保持BIS值为50~60。结果：与对照组相比,BIS组手术中血流动力学等监测指标更为平稳,BIS波动较小,镇静麻醉药丙泊酚总用量减少,两组相比有显著性差异（P〈0.05）。结论：以BIS反馈调控能指导麻醉用药量,获得更为平稳的血流动力学,维持适当的麻醉深度,并减少麻醉维持中麻醉药物用量。

Objective：To Evaluate the bispectral index（BIS） in monitoring the depth of anesthesia to guide anesthesia drugs in cardiac surgery.Methods： 30 patients of rheumatic heart disease undergoing valve replacement operation,randomly divided into two groups,each group of 15 cases.The control group according to the experience anesthesia drugs continuous pump injection Propofol,BIS group to trace pump continuous narcotic drugs pump injection Propofol maintenance of anesthesia and,depending on the depth of guardianship instrument monitoring BIS value adjustment pump injection speed to maintain the depth of anesthesia,maintain BIS in the value of 50~60.Results： Compared with control group in the operation,BIS group hemodynamic monitoring showed more smoothly,BIS less jerky,Propofol total amount decrease.The two groups showed the significant difference（P0.05）.Conclusion： With BIS as feedback control can guide anesthesia gain much smoother hemodynamics,maintain proper depth of anesthesia and reduce anesthesia maintain anesthetic drugs dosage.