复方阿嗪米特肠溶片联合多潘立酮治疗功能性消化不良疗效观察

Effect of complex Azintamide Enteric tablet combined with Domperidone on patients with functional dyspepsia

目的:观察复方阿嗪米特肠溶片联合多潘立酮治疗功能性消化不良(FD)的临床疗效。方法:75例功能性消化不良患者随机分治疗组40例,对照组35例。两组均应用多潘立酮片10mg/次,3次/d,餐前30min服。治疗组在应用多潘立酮的基础上加服复方阿嗪米特肠溶片,2粒/次,3次/d,餐后服用。疗程均为4周,观察临床症状变化及缓解情况。结果:治疗组症状缓解总有效率达95%,与对照组总有效率80%比较差异有统计学意义(P<0.05)。结论:复方阿嗪米特肠溶片联合多潘立酮治疗功能性消化不良(FD)疗效较好且安全,临床疗效优于单用多潘立酮。

Objetive：To investigate the clinical efficacy of complex Azintamide Enteric tablet combined with Domperidone in functional dyspepsia.Methods： 75 patients were divided into two groups randomly,complex Azintamide Enteric tablet combined with Domperidone treatment group（40 patients）,and control group（35 patients）.Patients of the two groups took Dompridone（10mg）30minutes before meals,Tid for 4 weeks.Meanwhile patients in the treatment group were given 2 complex Azintamide Enteric tablets after meals,Tid.The changes of clinical symptoms and progress of relief were recorded.Results：The total effective rate of symptom relief in the treatment group was 95%,compared to the 80% in control group.There was significantly statistical difference（P0.05）.Conclusions：Complex Azintamide Enteric tablet combined with Domperidone is safe in the treatment of functional dyspepsia,and more effective than Domperidone only.