新生儿窒息致多脏器功能不全临床分析

Clinical analysis on multiple organ disfunction syndrom caused by neonatal asphyxia

目的:了解新生儿窒息后多脏器功能不全综合征(MODS)的发生率、临床特点及相关危险因素。方法:分析169例窒息新生儿MODS的发生率及相关危险因素。结果:(1)窒息后器官功能不全发生率依次为脑(53.8%)、肺(45.6%)、心(30.2%)、肝(18.3%)、胃肠(13.0%)、肾(11.2%)。(2)重度窒息致MODS发生率高于轻度窒息。(3)MODS发生率及严重程度与围产因素密切相关。结论:重视围产期保健,分娩前严密监测,加强产儿合作,及时合理复苏和重视复苏后监测是降低MODS的关键。

Objective：To explore the rate,clinical characteristics and risk factors refered to multiple organ disfunction syndrom（MODS） caused by neonatal asphyxia.Results： ①The rate of organ disfunction after asphyxia were： brain 53.8%,lung 45.6%,heart 30.2%,liver 18.3%,gastrointestine 13.0% and kidney 11.2%.②The severe asphyxia showed the higher rate of MODS than that of the mild asphyxia.③The rate and severe degree of MODS were correlated to perinatal factors closely.Conclusion： In order to decrease the rate of MODS,it is key to pay attention to the health care of gerinatal period,prenatal detecting,cooperation between pediatrics and obstetrics,as well as rational resuscitation after asphyxia.