^99Tc^m-MIBI亲肿瘤延迟断层显像对肺占位病灶的诊断价值

Diagnostic value of tumor positive delay tomogram imaging with ^99Tc^m MIBI for pulmonary neoplasms

目的探讨^99Tc^mMIBI亲肿瘤延迟断层显像在肺部占位病灶中的诊断价值。方法对28例肺部占位患者静脉注射740MBq^99Tc^mMIBI后1h行延迟断层显像，以占位病灶（T）／对测相应部位或邻近正常组织（N）的摄取比值T／N〉1．31为恶性病变标准对肺部占位病灶进行良、恶性判断。结果肺占位在良性占位组显像剂浓聚多数轻度增强，恶性占位组多数明显增强。肺占位诊断恶性病灶的灵敏度为76．9％，特异度为86．7％，假阳性为13.3％，假阴性为23．1％。结论^99Tc^mMIBI亲肿瘤延迟断层显像以其无创、灵敏、图像质量及特异性较高的优点，可作为在肺占位病灶良、恶性鉴别诊断的重要辅助检查手段。

Objective To investigate the diagnotic value of tumor positive delay tomogram imaging with ^99Tc^mmethoxyisobutylisonitrile （MIB1） for puhnonary neoplasm. Methods Twenty-eight eases pulmonary neoplasms traded by ^99Tc^mMIBI imaging,then performed tomogram imaging after lh.By the uptake ratio value exceeding 1.31 between pulmonary neoplasm（T）and nomlal tissue on the opposite side or vicinity tissue （N）, benign or malignant was diagnosted. Results The malignant pulmonary neoplasm had abnormal high uptake, but benign pulmonary neoplasm had light uptake. The sensitivity and specificity of ^99Tc^mM1BI imaging for the malignant pulmonary neoplasm were 76.9% and 86.7% respectively, the false positive and false negative rate were 13.3% and 23.1% respectively. Conclusions Tumor positive delay tomogram imaging with ^99Tc^mMIBI for pulmonary neoplasm is an important detection in differentiating benign and malignant, it has high sensitivity, specificity, picture quanlity and no wound again.