胰激肽原酶治疗糖尿病周围神经病变的疗效观察

Study on the Effect of Pancreatic Kininogenase in Treating Diabetic Peripheral Neuropathy

目的:观察和评价注射用胰激肽原酶在治疗糖尿病周围神经病变方面的作用。方法:将108例糖尿病周围神经病变患者随机分为两组,在降糖治疗的基础上,治疗组(54例)用注射用胰激肽原酶治疗。对照组(54例)肌注维生素B1及维生素B12治疗,疗程为30d。结果:对照组总有效率61.1%,显效率29.6%;治疗组总有效率92.6%,显效率为48.1%,两组间差异有显著性(P<0.01)。结论:注射用胰激肽原酶在治疗糖尿病周围神经病变方面有明显的治疗效果。

Objective：To investigate the clinical efficacy of pancreatic kininogenase in treating diabetic peripheral neuropathy.Methods：108 patients with the diabetic peripheral neuropathy were randomly divided into a treatment group and a control group.Based on the glycemic control,Treatment group（54 cases）was treated with pancreatic kininogenase,the control group（54 cases） with vitamin B1 and vitamin B12 for 30 days.Results：The marked effective rate was 29.6% and total effective rate was 61.1% in the treatment group,while 48.1% and 92.1% in the treatment group（P0.01）.Conclusion：The pancreatic kininogenase is effective in the treatment of the diabetic peripheral neuropathy.