早发型重度子痫前期125例临床分析

Clinical Analysis of Pregnancy Termination in Early Onset Severe Preeclampsia

目的:探讨早发型重度子痫前期终止妊娠时机与围生结局的关系,进一步研究早发型重度子痫前期的期待保守治疗的临床意义。方法:回顾分析我院2001年1月至2009年12月住院分娩125例早发型重度子痫前期孕妇的临床资料,按入院妊娠孕周分为3组:<28周组16例,28～32+6周组22例,33～34+6周组87例。结果:期待治疗过程中3组出现并发症子痫、Hellp综合征、急性肾损害、胎盘早剥比较有明显的统计学差异(P<0.05);围生儿病率、围生儿死亡率明显降低,差异有统计学意义(P<0.05)。结论:早发型重度子痫前期采取期待治疗,延长分娩孕周,可改善母儿结局。

Objective：To study the relationship between the timing of pregnancy termination on maternal and perinatal outcome in early-onset severe pre-eclampsia. Methods：125 cases of early-onset severe pre-eclampsia admitted to our hospital from Jan.2001 to Dec.2009 were retrospectively investigated.They were divided into three groups：Lower 28 week;28～32＋6 week and 33～34＋6 pregnancy week group.Compared with their perinatal outcome. Results：There was significant diference among the three groups of mother＇s complication in expectant management（P〈0.05）.There was significant diference among the three groups in The perinatal infant mortality（P〈0.05）. Conclusion：The expectant management can be suitable for part of pregnant women who get early-onset severe pre-eclampsia,which can improve the result of perinatal infant and is safe also for the pregant women.