摘要
目的观察肌肉注射喘可治治疗慢性阻塞性肺疾病急性发作(AECOPD)患者的疗效和安全性。方法将AECOPD患者90例随机分为治疗组60例和对照组30例,两组患者入院后进行常规持续低流量吸氧、解痉平喘、抗感染、化痰、维持水电质平衡及对症处理。治疗组在对照组治疗基础上,加用喘可治注射液肌肉注射治疗,疗程均为一周,比较治疗前后两组的肺功能指标第1秒用力呼气量(FEV1)、用力肺活量(FVC)、第1秒用力呼气容积占用力肺活量百分比(FEV1/FVC)的改善、疗效及不良反应。结果治疗组在改善肺功能及临床症状方面优于对照组,两组比较,差异均有统计学意义(P<0.05);在不良反应方面,观察期间,治疗组未发现明显的不良反应。结论喘可治注射液治疗AECOPD安全、有效,值得临床进一步推广使用。
Objective To observe the efficacy and safety of muscular injection of chuankezhi on acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods 90 cases of AECOPD were randomized into a treatment group(60 cases)and a control group(30 cases).After admission,all the patients in two groups received the treatment of continued low flow oxygen,spasmolysis,relieving asthma,anti-infection,resolving phlegm and maintaining electrolyte balance,as well as symptomatic management.In treatment group,on the basis of the treatment as control group,muscular injection of chuankezhi was added.The duration of treatment was one week.The improvements in FEV1,FVC,FEV1/FVC,efficacy and adverse reaction were compared before and after treatment in two groups.Results The improvements in pulmonary function and clinical symptoms were superior to control group,indicating significant statistical difference(P0.05).In terms of adverse reaction,during the observation,no apparent adverse reaction occurred in treatment group.Conclusion Chuankezhi injection is safe and effective on AECOPD and it deserves to be further promoted in clinical practice.
出处
《世界中西医结合杂志》
2011年第3期225-226,共2页
World Journal of Integrated Traditional and Western Medicine
关键词
喘可治
慢性阻塞性肺疾病
急性期
Chuankezhi
Chronic Obstructive Pulmonary Disease(CPOD)
Acute Exacerbation