无症状性脑梗塞MRI、危险因素及临床意义的研究

Changes of MRI and Vascular Risk Factors in Patients with Silent Cerebral Infarction

目的：探讨５１ 例无症状性脑梗塞的头 Ｍ Ｒ Ｉ改变及血管危险因素。方法：全部病人均进行头 Ｍ Ｒ Ｉ扫描，记载有关病史，并进行详细的神经系统检查。 Ｍ Ｒ Ｉ改变 Ｔ１ 加权低信号， Ｔ２ 加权高信号，病灶直径在５ｍ ｍ 以上者诊断为无症状性脑梗塞。结果： Ｍ Ｒ Ｉ检出率 ９０２％ 。 Ｍ Ｒ Ｉ梗塞灶主要位于半卵圆中心（６１４２％ ），侧脑室周围（２１６５％ ），基底节区（８７％ ）。有高血压病史者检出的梗塞灶最多（７７３６％ ），其次为糖尿病（３０１２％ ），心脏疾病（２５７８％ ）。并且随着年龄增加， Ｍ Ｒ Ｉ检出率增高。结论：无症状性脑梗塞的危险因素与脑血管病基本相同，早期发现积极治疗无症状性脑梗塞对脑血管病的发生具有重要意义。

Objective:We undertook this study to evaluate the changes of Magnetic Resonance Imaging and vascular risk factors in silent cerebral infarction. Methods:MRI was obtained from 51 patients. We evaluated the neurological status by taking detailed medical history and neurological examination. Silent cerebral infarction was defined as hyperintense lesion on T 2 weighted images with corresponding hypointense lesion >5 cm diameter on T 1 weighted images. Results:The detection rate was 90.2% in all patients with silent infarcts by MRI. MRI lesions were mainly located in centrunsemiovale (61.42%), periventricular(21.65%), and basal genglia (8.7%). Lesions were revealed by MRI in 7%~36% of the patients with hypertension, in 30.12% of those with diabetes, and in 25.78% of those with cardiac diseases. The silent infarcts on MRI increased with age. The risk factors of silent infarcts were similar with those of cerebral vascular diseases. Conclusion:Early diagnosis and treatment of silent infarcts are important for preventing cerebral vascular disease.\;Conclusion:Early diagnosis and treatment of silent infarcts are important for preventing cerebral vascular disease.\;Early diagnosis and treatment of silent infarcts are important for preventing cerebral vascular disease.\;