高温预处理后大强度负荷对大鼠肾脏热休克蛋白70过氧化物歧化酶丙二醛及尿蛋白的影响

The effection of intensity load to the rat's kidney heat shock protein-70 with dismutase malonaldehyde of peroxide and urokinase protein after high temperature treatment

目的:研究高温预处理大强度负荷大鼠肾脏HSP70的表达,对尿蛋白产生的影响。方法:SD大鼠48只分为室温安静组、室温27m/min组、室温恢复组、高温预处理安静组、预处理27m/min、高温恢复组,运动后即刻处死取材。结果:(1)高温预处理安静组HSP70较对应的室温安静组显著表达;(2)大强度负荷运动后即刻和恢复2h后,高温组尿蛋白的产生显著低于对应的室温组。结论:肾脏HSP70的高度表达,提高了肾小球、肾小管对运动应激的耐受力,降低了尿蛋白的产生。

In order to study the intensity loading in high temperature treatment influencing the rat＇s kidney HSP-70 and urokinase protein,this paper take some comparative experiments by divided 48 rats into 6 groups.The results show that the high level HSP-70 promotes the ability of response to run the renal glomerulus and tubule,and decreases the production of albuminuria.