摘要
目的探讨雾化吸入布地奈德对哮喘儿童肺功能的改善及安全性。方法选择95例6～48月的哮喘患儿持续(6月)吸入布地奈德,每日250μg,2次/d,治疗前及治疗6月后分别测定各项肺功能指标、血皮质醇及骨密度。结果治疗6月后,肺功能有明显改善,血皮质醇及骨密度无明显变化。结论吸入布地奈德能改善哮喘患儿肺功能,降低气道高反应性,对患儿肾上皮质功能及骨密度未见显著影响。
Objective To investigate the safety and improvement to young children with asthma inhalation budesonide . Methods 95 cases children with asthma and the age are between 6 - 48 months. The patients were inhalated bndesonide for 6 months. The pulmonary function, hydrocortisone in blood plasm and bone density were detected. Results After accept the treatment for 6 months the pulmonary function were improved obviously and the hydrocortisone in blood plasm and bone density did not make change. Conclusion In inhalation budesonide for 6 months can improve the children＇s pulmonary function, decrease airway hyperreactivity and do not influence hydrocortisone and bone density.
出处
《湘南学院学报（医学版）》
2011年第1期13-15,共3页
Journal of Xiangnan University（Medical Sciences）
基金
湖南省卫生厅科研项目(B2008096)
