恩诺沙星配伍蒲甘散对异育银鲫败血症的疗效研究

Study on Curative Effect of Enrofloxacin Compound With Pu Powder to Bacterial Septicemi of Carassius Auratus Gibelio

为探讨治疗异育银鲫细菌性败血症的有效药物及治疗方法,通过体外抑菌和药饵饲喂试验,比较研究恩诺沙星、蒲甘散单方给药及恩诺沙星与蒲甘散配伍给药对异育银鲫细菌性败血症的疗效.体外抑菌的M IC及MBC结果表明:恩诺沙星与蒲甘散联合使用对嗜水气单胞菌的抑制作用要明显高于单方药物的抑制作用.口服药饵试验测定的药物保护率表明,恩诺沙星单方给药,恩诺沙星与蒲甘散配伍给药的试验组与未给药饵的对照组相比较,差异均为极显著(P<0.01),且以恩诺沙星与蒲甘散按1∶6比例配伍给药疗效最佳,对异育银鲫细菌性败血症有效率可达91.8%.

To study the better drugs and effective treatment method to bacterial septicemi of Carassius auratus gibelio, this paper used Enrofloxacin, Pu Powder and Enrofloxacin compound with Pu Powder respectively to cure the disease to compare the effect accroding to studying the inhibition out of body and the cure rate fed with drugs. The result of MIC and MBC showed that the inhibition of the test groups of enrofloxacin compound with Pu Powder was obviously higher than groups of single drug. The efficiency of oral test showed that the level of groups of enrofloxacin and enrofloxacin compound with Pu Powder was significantly higher than the contrast group （ P 〈 0. 01 ）. 1 ： 6 as the proportion of com- pound enrofloxacin to Pu Powder was the best proportion, and the cure rate of this group was 91.8%.