慢性病毒性肝炎胆囊声像异常与肝组织炎症坏死程度的关系

Correlation of abnormal gallbladdler sonography with degree of inflammatory necroses in patients with chronic hepatitis

目的：探讨慢性病毒性肝炎胆囊声像异常与肝组织炎症程度的关系。方法：分析了112例慢性肝炎患者胆囊壁厚度、光滑度、胆囊大小异常、合并胆囊结石及息肉的发生率，并与肝组织病理炎症坏死程度分级进行比较及相关分析。结果：胆囊声像异常总发生率为57.14％。胆囊壁厚度在轻、中、重度慢性肝炎相互间比较差异均有显著性，与肝脏炎症坏死程度呈显著性正相关（r＝0.67，P＜0.0001）。胆囊壁不光滑及胆囊大小异常发生率在中重度与轻度慢性肝炎比较差异有显著性，而合并胆囊结石及息肉的发生率在各组间比较差异均无显著性。结论：超声评价胆囊壁厚度、光滑度及胆囊大小异常对判断慢性病毒性肝炎病情程度，特别是鉴别轻度与中重度慢性肝炎有重要参考价值。

Objective: To study the condation of abnohal gallbladder sonography with degree of inflaminaion of hepatic tissue in Patients with cboc hepatitis. Methods: Thckness of gallb1adder wall and Other abnormal sonographic drifestations of gallbladde wer studied in 1l2 patients with cbonic viral hePaitis, and findings were compared with histological hepatic iodaininatory changs. Results: The incidence of abnormal gallbladder sonography was 57. l4%. The thickness of the gallbaddr wall was significanil fferent a mong whld, mederate and severe chronic hePatihs, and it demonstraed signilicant positive corralation with the degree of liver indanunaion and necrosis(r = 0.67, P < 0.0001 ). The incidence of rowt gallbladder wall and abnorinal size of gallhladde were also sighficanil different between mild and moderat-severe chronic hepatitis, whereas the incidence of gal stones and polypi of gallbladder wer no sied cantly different among different severity of chronic hepaihs. Conclusions: Ultrasound measurement of the gallbladder wall thickness,sonograpic evaluaion of the sinthness of gallbladder wall and the size of gallhladdr were useful in the judgment of degnes of inflaminaion and necrosis of hepatic tissue, especially in the differentiation of hald 1nd moderate-to-severe degree of chronic hepaihs.