自拟消溃愈肠方配合保留灌肠治疗溃疡性结肠炎52例疗效观察

Effective observation on treating 52 cases of ulcerative colitis by Xiaokui Yuchang prescriptions plus retention enema

目的:观察消溃愈肠方配合保留灌肠治疗溃疡性结肠炎的疗效。方法:选择溃疡性结肠炎患者98例,随机分为两组。治疗组52例,以消溃愈肠方(乌梅、败酱草、秦皮、黄连、木香、益母草、炒白芍、炒枳实、炒山楂、炒白术、党参、茯苓、葛根、甘草)水煎服,并以煎液调入云南白药、锡类散保留灌肠;对照组46例,给予口服柳氮磺吡啶片,配合氢化可的松保留灌肠。观察比较两组近期完全缓解率、总有效率、2年未复发率。结果:近期完全缓解率治疗组为71.15%、对照组为39.13%,总有效率治疗组为96.15%、对照组为82.61%,两组比较差异均有显著性意义(P<0.05);2年未复发率治疗组为83.78%,对照组为11.11%,两组比较差异有显著性意义(P<0.01)。结论:消溃愈肠方配合保留灌肠治疗溃疡性结肠炎有较好疗效。

Objective： To observe the effects on treating ulcerative colitis by Xiaokui Yuchang prescriptions combined with retention enema. Methods： Select 98 cases of patients with ulcerative colitis, randomly divide them into two groups. Treatment group for 52 cases, boiling according to Xiaoku Yuchang prescriptions （ebony, baijiangcao, qin skin, berberine, woody, motherwort, fried white peony root, fried citrus aurantium, fried hawthorn, fried atractylodes, codonopsis, poria, kudzu, licorice）, the liquid was added with Yunnanbaiyao, Xileisan retention enema; 46 cases of control group taking sulfasalazine tablets, plus hydrocortisone retention enema. Observing and comparing the recently complete remission rate, total effective rate, recurrence rate during two years of the two groups. Results： The recently complete remission rate of treatment group was 71.15%, the control group for 39.13%, the total effective rate of treatment group was 96.15%, the control group for 82.61%, the difference between the two groups had extraordinary significance （P〈0.05）; Recurrence rate during two years was 83.78%, the control group was 11.11%, the difference of the two groups compared with each other had extraordinary significance （P〈0.01）. Conclusion： The treatment of Zini Xiaokui Yuchang prescriptions combined with retention enema ulcerative colitis had a good effect.