摘要
目的:了解我院药品不良反应(ADR)的发生情况及影响因素,以促进临床合理用药。方法:应用Excel软件,对2007年7月1日~2010年6年30日我院收集到的852份ADR报告,分别就患者性别、年龄、涉及的药品种类、器官或系统及临床表现等进行分类统计。结果:852份ADR报告中涉及的药品共有278个品种,抗感染药所占比例最高,共74种,占26.62%;给药途径以静脉用药为主,共450例,占49.29%;严重ADR 89例,占10.45%。结论:应重视ADR监测工作,加强对患者用药过程观察,保证患者用药安全、合理,减少ADR的发生。
Objective:To study the occurrence of adverse drug reactions (ADR) and their relevant factors in our hospital in order to improve the rational drug use in the clinic. Method: 852 cases of ADR reports collected in the hospital during 1 July 2007 to 30 June 2010 were retrospectively analyzed in respect of patients' gender and age, drug kinds, ADR- involved organs or systems and clinical manifestations, etc. by using Excel. Result:Among the 852 cases, 278 kinds of drugs were related. Anti-infectious drugs were the highest in the incidence rate of ADRs (74 kinds, 43.81% ). The main route of medication was by vein (450 cases, 49.29% ). The severe ADRs were 89 cases, occupying 10.45%. Conclu sion : More importance should be attached to the monitoring of ADRs and strengthening the observation of drug use to reduce or avoid the occurrence of ADRs.
出处
《药物流行病学杂志》
CAS
2011年第3期119-121,共3页
Chinese Journal of Pharmacoepidemiology
关键词
药品不良反应
报告
合理用药
Adverse drug reaction
Analysis
Rational drug use