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药物性肝损伤的因果评价方法 被引量:9

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摘要 肝脏是药物浓集、转化、代谢的主要器官。随着全球新药的迅速市场化,患者接触新型化合物机会的增加,药物性肝损伤(Drug—induced Liver Injury,DILI)的发病呈上升趋势,在美国和北欧国家,DILI是急性肝衰竭的首要原因。目前,已发现近1000种药品与肝损伤相关,肝损伤已是导致药品撤市的最常见原因。
作者 陈雅敏 邹琛
出处 《药物流行病学杂志》 CAS 2011年第3期152-155,共4页 Chinese Journal of Pharmacoepidemiology
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